Cyclobenzaprine with ibuprofen versus ibuprofen alone in acute myofascial strain: a randomized, double-blind clinical trial
Generally, it is not safe to take two muscle relaxers together. However, this may change depending on the instruction of a medical doctor. One must intake pills as prescribed, and if there is no specific “signa” that two of these drugs should be taken, one should not take two of them together. According to the US Food and Drug Administration, drug interactions occur when two or more drugs are taken together. A medical doctor may prescribe two drugs that are supposed to be taken together to achieve optimal results.
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Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Ibuprofen belongs to the drug class Nonsteroidal anti-inflammatory drug (NSAID), which helps treat fever and pain caused due to various disorders. Ibuprofen can be used in combination with other medications as well.
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In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at FDA-1088 or at /medwatch. The dose can flexeril make you gain weight of this medicine will be different for different patients. The following information includes only the average doses of this medicine.
If both are consumed in large doses, they may slow down breathing and leave the person sedated. Other side effects include headache, nausea, tiredness, nervousness, heartburn, constipation, stomach ache, and more. However, physical therapy can also help reduce the risk of tolerance to cyclobenzaprine. After all, the muscle relaxant is supposed to be taken short-term only. Generally speaking, a co-prescription of cyclobenzaprine and ibuprofen is common in cases of neck and back pain. That’s because the former is a relaxant that eases muscle pain, and the latter is a non-steroidal anti-inflammatory drug (NSAID) that works as a general analgesic.
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To view an interaction report containing 4 (or more) medications, please sign in or create an account. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum. A long-acting formulation of cyclobenzaprine has been introduced and is believed by some clinicians to have a lower side effect profile than the immediate-release formulation of this drug.
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Examples of centrally acting agents include baclofen, carisoprodol, methocarbamol, and tizanidine. Zoloft is one of the selective serotonin reuptake inhibitors (SSRIs) and it is mainly used for the treatment of major depressive disorder. As of 2019, there are around 1,000 drug interactions with this medication and these include muscle relaxants. Zoloft interactions with these drugs increase the risk of quite a health condition known as Serotonin Syndrome. The symptoms of this syndrome include seizures, hallucinations, increased heart rate, fever, spasms, nausea, cramps, in-coordination, and diarrhea.
Naproxen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins, and thereby reducing inflammation, pain, and fever. Both Skelaxin and Flexeril interact with tramadol (and other opioids)—there is an increased risk of serotonin syndrome as well as additive CNS depression. The most common side effects of Flexeril are drowsiness, dizziness, headache, and dry mouth.
- It peaks at around 3 to 4 hours, and then the effects begin to wear off.
- Consuming any medication together could be harmful for individual.
- Take this medication by mouth with or without food as directed by your doctor.
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Both of them are used for pain relief but have different mechanisms. In most cases, it is advised not to take an anti-inflammatory drug and a muscle relaxant simultaneously, as they might be contra-indicated. Since Flexeril is a muscle relaxant that shows the depressive activity of the CNS, it is not recommended to drive or do any dangerous activity under the influence of Flexeril. Combining this drug with alcohol may worsen the side effects you may observe. Modifying the drug dose without consulting a physician to amplify its impact is also not recommended. They belong to two different drug classes – muscle relaxant and benzodiazepine, respectively.